KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYRK3
All Species:
25.76
Human Site:
Y32
Identified Species:
40.48
UniProt:
O43781
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43781
NP_001004023.1
588
65714
Y32
R
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Chimpanzee
Pan troglodytes
XP_524527
588
65774
Y32
R
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Rhesus Macaque
Macaca mulatta
XP_001086117
588
65769
Y32
R
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Dog
Lupus familis
XP_537131
637
71340
Y82
C
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q922Y0
586
65553
Y32
R
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Rat
Rattus norvegicus
Q4V8A3
586
65492
Y32
R
R
L
G
D
G
V
Y
D
T
F
M
M
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511087
546
60615
H22
S
R
H
A
M
T
D
H
L
H
V
G
G
H
G
Chicken
Gallus gallus
Q5ZIU3
526
59419
D21
Q
V
Q
Q
L
F
E
D
N
S
N
K
R
T
V
Frog
Xenopus laevis
NP_001088793
567
63329
G19
A
A
V
R
Y
G
D
G
L
Y
D
S
Y
M
R
Zebra Danio
Brachydanio rerio
NP_001108400
581
65351
Y21
A
R
H
G
D
G
L
Y
D
S
Y
M
R
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83102
828
92722
F87
L
Q
Y
L
T
R
C
F
E
P
L
A
M
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023207
817
89866
L120
Q
G
H
R
N
P
A
L
G
S
G
N
T
L
T
Sea Urchin
Strong. purpuratus
XP_799140
561
63192
R21
N
L
Q
A
S
R
T
R
S
L
T
Q
G
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51566
467
54180
Baker's Yeast
Sacchar. cerevisiae
P14680
807
91227
L113
Y
P
P
Q
Y
D
D
L
N
S
N
E
S
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
85.7
N.A.
89.6
90.8
N.A.
57.9
59
65.3
63.4
N.A.
39
N.A.
40.5
54.7
Protein Similarity:
100
99.4
99.4
88.8
N.A.
93.5
94.2
N.A.
70.7
71.9
77.8
76.6
N.A.
50.9
N.A.
52.5
68.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
0
6.6
53.3
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
20
20
73.3
N.A.
40
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
14
0
0
7
0
0
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
7
20
7
47
0
7
0
0
7
54
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
40
0
0
0
0
% F
% Gly:
0
7
0
47
0
54
0
7
7
0
7
7
14
0
7
% G
% His:
0
0
20
0
0
0
0
7
0
7
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
7
7
40
7
7
0
7
14
14
7
7
0
0
20
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
47
47
7
0
% M
% Asn:
7
0
0
0
7
0
0
0
14
0
14
7
0
0
7
% N
% Pro:
0
7
7
0
0
7
0
0
0
7
0
0
0
0
0
% P
% Gln:
14
7
14
14
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
34
54
0
14
0
14
0
7
0
0
0
0
14
0
7
% R
% Ser:
7
0
0
0
7
0
0
0
7
27
0
7
7
0
0
% S
% Thr:
0
0
0
0
7
7
7
0
0
40
7
0
7
14
14
% T
% Val:
0
7
7
0
0
0
40
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
14
0
0
47
0
7
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _